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In a nested case-noncase study by Battini et al, 24 all signal detection methodologies and disproportionality statistics investigating the GLP-1 analogs, in particular, liraglutide and glicazide, agreed on its statistically significant potential antidepressant effect

2 CHAC1 as a central integrator of glutathione homeostasis, stress signaling and ferroptosis Glutathione homeostasis is essential for cellular and organismal health due to its central role in maintaining redox balance

doi:10.1038/s41598-018-37215-0 92